Braaksma M A, Poortinga F M, Aarnoudse J G
Department of Obstetrics and Gynaecology, University of Groningen, The Netherlands.
Pediatr Res. 2000 Jun;47(6):773-7. doi: 10.1203/00006450-200006000-00015.
Daily rhythmicity of renal blood flow (RBF) and urine flow (UF) was studied in fetal sheep between 121-125 d of gestation. Fetal arterial blood pressure, heart rate, UF, and right RBF were measured continuously for 24-h periods in 10 sheep. Rhythmic variations during a 24-h period were found for all variables studied. The rhythms of arterial blood pressure and heart rate were highly correlated, whereas an inverse correlation was found between arterial blood pressure with RBF and between arterial blood pressure with UF. These findings indicate that fetal RBF is not blood pressure dependent. Furthermore, fetal UF appears not to be mediated by pressure-dependent diuresis.
在妊娠121 - 125天的胎羊中研究了肾血流量（RBF）和尿流（UF）的每日节律性。对10只绵羊的胎儿动脉血压、心率、UF和右肾血流量进行了连续24小时的测量。在所研究的所有变量中均发现了24小时内的节律性变化。动脉血压和心率的节律高度相关，而动脉血压与RBF之间以及动脉血压与UF之间呈负相关。这些发现表明胎儿RBF不依赖于血压。此外，胎儿UF似乎不是由压力依赖性利尿介导的。
