Khrabrova A V, Zagrebin A O, Kosmachev A B, Kubarskaia L G, Lychakov A V, Libman N M, Savateeva T N, Titkova T A, Tonkopiĭ V D, Fil'ko O A, Khobotova Z I
Institute of Toxicology, Ministry of Public Health of the Russian Federation, St. Petersburg, Russia.
Eksp Klin Farmakol. 2000 Mar-Apr;63(2):21-3.
Experiments on rodents showed that pentifin, a muscarine antagonist belonging to the group of acetylene amines, possesses a pronounced antiparkinsonian activity. Pentifin is superior in the breadth of therapeutic action and tolerance characteristics to the conventional agents used for Parkinson's disease treatment.
对啮齿动物的实验表明,喷替芬是一种属于乙炔胺类的毒蕈碱拮抗剂,具有显著的抗帕金森病活性。在治疗作用范围和耐受性方面,喷替芬优于用于治疗帕金森病的传统药物。