Kosmachev A B, Tonkopiĭ V D, Podosinovikova N P, Zagrebin A O, Evdokimova E A, Libman N M, Petrov V V, Dolgo-Saburov V B
Institute of Toxicology, Ministry of Public Health of the Russian Federation, ul. Bekhtereva 1, St. Petersburg, 193019 Russia.
Eksp Klin Farmakol. 2000 Nov-Dec;63(6):15-7.
Haloperidol and dimethpromide exhibit the properties of dopamine antagonists in the experiments on Daphnia magna Straus (Crustaceae family). Haloperidol, in contrast to dimethpromide, does not significantly influence the toxic effect of apomorphine. It is suggested that acetylene aminoalcohol derivatives are selective ligands for one of the subtypes of dopamine receptors.
在对大型溞（甲壳纲）的实验中，氟哌啶醇和二甲丙嗪表现出多巴胺拮抗剂的特性。与二甲丙嗪不同，氟哌啶醇对阿扑吗啡的毒性作用没有显著影响。有人认为乙炔氨基醇衍生物是多巴胺受体亚型之一的选择性配体。
