Coleman A C, Mydlarz L D, Kerr R G
Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton 33431, USA.
Org Lett. 1999 Dec 30;1(13):2173-5. doi: 10.1021/ol991120i.
[formula: see text] Both in vivo and in vitro techniques have been developed to test putative intermediates in the biosynthetic pathway to the pseudopterosins, antiinflammatory compounds isolated from Pseudopterogorgia elisabethae. Furthermore, specific activity data we have obtained indicate that pseudopterosin A is a precursor to pseudopterosins B, C, and D. We conclude that in the biosynthesis xylose is attached to the diterpene skeleton to produce pseudopterosin A and is then aceylated to form pseudopterosins B-D.
