Edelman D A, Brenner W E, Mehta A C, Philips F S, Bhatt R V, Bhiwandiwala P
Am J Obstet Gynecol. 1976 May 15;125(2):188-95. doi: 10.1016/0002-9378(76)90591-3.
The efficacy, side effects, and complications of two intra-amniotic PGF2alpha dose schedules and the unaugmented intra-amniotic instillation of saline are compared. All three methods resulted in satisfactory rates of abortion within a relatively short period of time and within clinically acceptable rates of complications. Each method has its advantages and disadvantages. Further large comparative studies were needed.
比较了两种羊膜腔内前列腺素F2α给药方案以及未增加药物的羊膜腔内注入生理盐水的疗效、副作用和并发症。所有三种方法在相对较短的时间内均产生了令人满意的流产率,且并发症发生率在临床可接受范围内。每种方法都有其优缺点。需要进一步开展大规模的对比研究。