Hahnenberger R W
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1976 Apr 14;199(2):179-86. doi: 10.1007/BF02385214.
Cats with one normal eye and one eye with experimental glaucoma were trained to tolerate tonometry while conscious. They were then given the general anesthetic agents pentobarbital, ketamine, and CI-744 in the lowest and twice the lowest dosages which permitted tonometry in untrained cats. Pentobarbital lowered intraocular pressure (IOP) by 20-50%. Ketamine raised IOP by about 10%. CI-744 had essentially no effect on IOP. The two conpoments of CI-744, tiletamine (CI-634) and zolazepam (CI-716) were given individually in the doses in which they had been given as part of CI-744. Tiletamine had no effect on IOP, while zolazepam lowered IOP by about 10%.
对一只眼睛正常而另一只眼睛患有实验性青光眼的猫进行训练，使其在清醒状态下耐受眼压测量。然后给它们使用最低剂量以及最低剂量两倍的全身麻醉剂戊巴比妥、氯胺酮和CI - 744，这些剂量能使未训练的猫进行眼压测量。戊巴比妥使眼压（IOP）降低了20% - 50%。氯胺酮使眼压升高了约10%。CI - 744对眼压基本没有影响。CI - 744的两个成分替来他明（CI - 634）和唑拉西泮（CI - 716）以它们作为CI - 744一部分时的剂量单独给药。替来他明对眼压没有影响，而唑拉西泮使眼压降低了约10%。
