Grover CM, Posner S, Kupperman M, Washington EA
Department of Obstetrics, Gynecology and Reproductive Sciences, and Institute for Health Policy Studies, University of California San Francisco, California, San Francisco, USA
Prim Care Update Ob Gyns. 1998 Jul 1;5(4):178. doi: 10.1016/s1068-607x(98)00086-9.
Objective: To determine the incidence and costs for cases of idiopathic preterm labor followed by term delivery.Study Design: Patients hospitalized with preterm labor (N = 28,845) were identified in a dataset linking antepartum and delivery discharge abstracts of all women in California (N = 404,466) with a delivery related diagnosis from 1/1/93 to 11/19/93. Patients with multiple gestations, PROM, abruption, placenta previa, uterine anomalies, and other morbidities were excluded, leaving 19,897 study subjects. Birth outcomes were classified as term or preterm (<37 weeks). The incidence, hospital costs, and risk factors for hospitalization for preterm labor followed by term delivery were then determined using a retrospective nested case control design. Indirect costs of subsequent bedrest were estimated using data from the California Disability Insurance Fund.Results: Thirty-four percent of patients hospitalized with idiopathic preterm labor had term deliveries accounting for 2% of the pregnant population. Eighty-one percent of patients who were discharged undelivered after hospitalization delivered at term. These patients were significantly more likely to be Caucasian, privately insured, and older than patients who delivered preterm. A minimum of 45% of cases were estimated to be false diagnoses based on the relative risk of post-dates pregnancy between patients hospitalized with preterm labor and term controls. Costs totalled $4,995 per case with $2,335 in hospital costs and $2,497 in indirect costs from an average of 4 weeks of bedrest. Statewide costs for California were estimated to range from 24 to 48 million dollars annually for these potentially avertible hospitalizations.Conclusions: Hospitalization for idiopathic preterm labor with delivery at term is common, costly, and probably due to false diagnosis in a significant proportion of cases.
确定特发性早产后继足月分娩的发生率及成本。
在一个将加利福尼亚州所有女性(N = 404,466)的产前和分娩出院摘要相链接的数据集中,识别出因早产住院的患者(N = 28,845),这些患者在1993年1月1日至1993年11月19日期间有与分娩相关的诊断。排除多胎妊娠、胎膜早破、胎盘早剥、前置胎盘、子宫异常及其他疾病患者,留下19,897名研究对象。出生结局分为足月或早产(<37周)。然后采用回顾性巢式病例对照设计确定特发性早产后继足月分娩的住院发生率、医院成本及危险因素。使用来自加利福尼亚州残疾保险基金的数据估算后续卧床休息的间接成本。
因特发性早产住院的患者中有34%足月分娩,占妊娠人群的2%。81%住院后未分娩而出院的患者足月分娩。这些患者比早产患者更可能是白人、有私人保险且年龄较大。根据早产住院患者与足月对照者过期妊娠的相对风险估计,至少45%的病例被估计为误诊。每例成本总计4995美元,其中医院成本2335美元,平均4周卧床休息的间接成本2497美元。加利福尼亚州全州因这些可能可避免的住院治疗的成本估计每年在2400万至4800万美元之间。
特发性早产住院后继足月分娩很常见,成本高昂,且在很大一部分病例中可能是由于误诊。