Scherder E J, Van Someren E J, Bouma A, v d Berg M
Department of Clinical Neuropsychology, Vrije Universiteit, De Boelelaan 1109, 1081 HV, Amsterdam, The Netherlands.
Behav Brain Res. 2000 Jun 15;111(1-2):223-5. doi: 10.1016/s0166-4328(00)00170-4.
In previous studies, transcutaneous electrical nerve stimulation (TENS) improved cognition and behaviour in patients with Alzheimer's disease (AD). The rationale underlying these studies was that TENS could activate, e.g. the septo-hippocampal region and the hypothalamus through direct and indirect pathways. As these areas are also affected in normal aging, the present study examined the effects of TENS on cognition and behaviour in nondemented elderly persons. The results suggest an improvement in visual short-term and verbal long-term (recognition) memory, and semantic verbal fluency. Moreover, stimulated elderly persons felt less depressed. Limitations are discussed.
在先前的研究中，经皮电刺激神经疗法（TENS）改善了阿尔茨海默病（AD）患者的认知和行为。这些研究的基本原理是，TENS可以通过直接和间接途径激活，例如隔区-海马区和下丘脑。由于这些区域在正常衰老过程中也会受到影响，本研究调查了TENS对非痴呆老年人认知和行为的影响。结果表明，视觉短期记忆、言语长期（识别）记忆和语义言语流畅性有所改善。此外，接受刺激的老年人抑郁情绪减轻。文中讨论了研究的局限性。
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