Savage R B, Hussey M J, Hurie M B
Madison Department of Public Health, Madison, Wisconsin 53709, USA.
Public Health Nurs. 2000 May-Jun;17(3):202-6. doi: 10.1046/j.1525-1446.2000.00202.x.
This paper reports the success of outreach efforts to immunize adults at high risk of acquiring hepatitis B virus (HBV) infection. Local health department testers recruited clients when they sought anonymous HIV testing. Interested clients were serologically tested for HBV infection. Susceptibles were offered a free hepatitis B vaccine. Of 189 clients who were tested, 161 (86%) were susceptible to HBV infection and 140 (74%) were men who have sex with men (MSM). Of the susceptibles, 82 (51%) started the hepatitis B vaccine series. Sixty-five (80%) received three doses of hepatitis B vaccine and an additional 10 (12%) received two doses. Completing the hepatitis B vaccine series was associated with being a MSM (odds ratio [OR] 8.8, confidence interval [CI] 1.5-56.0) and with not being an injection drug user (IDU) (OR 0.2, CI 0.02-1.0). One way to provide hepatitis B vaccine to MSM is to attach an immunization program to a successful anonymous HIV testing program. The feasibility of implementing such programs would increase if public vaccine policymakers made more federally purchased hepatitis B vaccine available for adults.
本文报告了为感染乙型肝炎病毒（HBV）高风险的成年人开展免疫接种外展工作所取得的成功。当地卫生部门的检测人员在客户寻求匿名HIV检测时招募他们。对感兴趣的客户进行HBV感染的血清学检测。对易感者提供免费的乙型肝炎疫苗。在接受检测的189名客户中，161名（86%）对HBV感染易感，其中140名（74%）是男男性行为者（MSM）。在易感者中，82名（51%）开始接种乙型肝炎疫苗系列。65名（80%）接种了三剂乙型肝炎疫苗，另有10名（12%）接种了两剂。完成乙型肝炎疫苗系列接种与成为男男性行为者（优势比[OR]8.8，置信区间[CI]1.5 - 56.0）以及不是注射吸毒者（IDU）（OR 0.2，CI 0.02 - 1.0）有关。为男男性行为者提供乙型肝炎疫苗的一种方法是将免疫接种计划与成功的匿名HIV检测计划相结合。如果公共疫苗政策制定者提供更多联邦采购的乙型肝炎疫苗供成年人使用，实施此类计划的可行性将会提高。
