Yee L J, Rhodes S D
Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, Department of Infectious and Tropical Diseases, Keppel Street, London WC1E 7HT, UK.
Sex Transm Infect. 2002 Oct;78(5):374-7. doi: 10.1136/sti.78.5.374.
Hepatitis B infection (HBV) is prevalent among men who have sex with men (MSM) and may lead to significant morbidity and death. Although an effective vaccine exists vaccination rates among MSM are low. We conducted a systematic review to synthesise the various findings from empirical correlational studies to understand HBV vaccination and series completion among MSM.
We systematically searched the Medline, PubMed, EMBASE, CINAHL, ERIC, and Web of Science databases to identify the breadth of published studies pertaining to HBV vaccination among MSM and to synthesise findings from these studies to better identify common themes that may direct future research and intervention approaches.
Eight papers specifically addressed correlates of HBV vaccination among MSM. Six domains were identified as predictors of vaccination: (1) demographic variables such as younger age and higher education level; (2) knowledge of the vaccine; (3) access to health care; (4) level of "outness" regarding one's same sex sexual orientation; (5) behavioural factors including sexual and drug use behaviour; and (6) psychosocial variables. Three papers addressed predictors of vaccine series completion among MSM, observing two main domains: (1) demographic variables such as younger age and higher income level; and, (2) behavioural factors including sexual and health promotion behaviours.
Continued educational efforts, creation of environments that facilitate proper risk factor evaluation, and access to low cost vaccine may facilitate vaccine uptake. Although we observed important trends in the studies we reviewed, there is a lack of empirical research regarding this important public health issue.
乙型肝炎感染(HBV)在男男性行为者(MSM)中普遍存在,可能导致严重发病和死亡。尽管有有效的疫苗,但MSM中的疫苗接种率较低。我们进行了一项系统综述,以综合实证相关性研究的各种结果,了解MSM中的HBV疫苗接种及系列接种情况。
我们系统检索了Medline、PubMed、EMBASE、CINAHL、ERIC和Web of Science数据库,以确定已发表的有关MSM中HBV疫苗接种研究的广度,并综合这些研究的结果,以更好地确定可能指导未来研究和干预方法的共同主题。
八篇论文专门探讨了MSM中HBV疫苗接种的相关因素。确定了六个领域作为疫苗接种的预测因素:(1)人口统计学变量,如年龄较小和教育水平较高;(2)对疫苗的了解;(3)获得医疗保健的机会;(4)对自身同性性取向的“公开程度”;(5)行为因素,包括性行为和药物使用行为;(6)心理社会变量。三篇论文探讨了MSM中疫苗系列接种的预测因素,观察到两个主要领域:(1)人口统计学变量,如年龄较小和收入水平较高;(2)行为因素,包括性行为和健康促进行为。
持续的教育努力、营造便于进行适当风险因素评估的环境以及获得低成本疫苗可能会促进疫苗接种。尽管我们在所审查的研究中观察到了重要趋势,但对于这个重要的公共卫生问题仍缺乏实证研究。