Structure-toxicity relationships of 2,6,7-trioxabicyclo(2.2.2)octanes and related compounds.

Suppr

超能文献

作者信息

Casida J E, Eto M, Moscioni A D, Engel J L, Milbrath D S, Verkade J G

出版信息

Toxicol Appl Pharmacol. 1976 May;36(2):261-79. doi: 10.1016/0041-008x(76)90006-5.

DOI:10.1016/0041-008x(76)90006-5

PMID:1084063

Abstract

摘要

相似文献

Structure-toxicity relationships of 2,6,7-trioxabicyclo(2.2.2)octanes and related compounds.

Toxicol Appl Pharmacol. 1976 May;36(2):261-79. doi: 10.1016/0041-008x(76)90006-5.

Structure--toxicity relationships of 1-substituted-4-alkyl-2,6,7-trioxabicyclo[2.2.2.]octanes.

Toxicol Appl Pharmacol. 1979 Feb;47(2):287-93. doi: 10.1016/0041-008x(79)90323-5.

2,6,7-Trioxabicyclo[2.2.2]octanes: chemistry, toxicology and action at the GABA-gated chloride channel.

Adv Biochem Psychopharmacol. 1988;45:109-23.

[Toxicity, hazard and nature of the biological action of methylcyclopentadiene dimer].

Gig Tr Prof Zabol. 1981 May(5):45.

Distribution and metabolic fate in mammals of the potent convulsant and GABA antagonist t-butyl-bicyclophosphate and its methyl analog.

Toxicol Appl Pharmacol. 1978 Nov;46(2):411-20. doi: 10.1016/0041-008x(78)90086-8.

Dinitrosopentamethylenetetramine.

IARC Monogr Eval Carcinog Risk Chem Man. 1976;11:241-5.

[Phytopharmacological investigation of endomide and its metabolites. Correlation between phytotoxicity, zootoxicity and lipophilic properties (author's transl)].

Arch Pharm (Weinheim). 1976 Oct 10;309(10):822-8. doi: 10.1002/ardp.19763091009.

Evaluation of the subacute toxicity and teratogenicity of anatoxin-a.

Toxicon. 1980;18(5-6):684-8. doi: 10.1016/0041-0101(80)90100-2.

Synthesis and analgesic activity of some 5-(4-hydroxyphenyl)-2-azabicyclo[3.2.1]octanes.

J Med Chem. 1980 Jul;23(7):726-9. doi: 10.1021/jm00181a005.

Bicycloorthocarboxylate convulsants. Potent GABAA receptor antagonists.双环邻羧酸酯类惊厥剂。强效γ-氨基丁酸A受体拮抗剂。

Mol Pharmacol. 1985 Sep;28(3):246-53.

引用本文的文献

History of Organophosphorus Compounds in the Context of Their Use as Chemical Warfare Agents.有机磷化合物作为化学战剂使用背景下的历史

Molecules. 2025 Apr 4;30(7):1615. doi: 10.3390/molecules30071615.

GABA receptor subtype selectivity of the proconvulsant rodenticide TETS.TETS 这种致惊厥性的啮齿动物杀鼠剂对 GABA 受体亚型的选择性。

Arch Toxicol. 2018 Feb;92(2):833-844. doi: 10.1007/s00204-017-2089-4. Epub 2017 Oct 16.

Tetramethylenedisulfotetramine: pest control gone awry.四亚甲基二砜四胺：失控的害虫防治

Ann N Y Acad Sci. 2016 Aug;1378(1):68-79. doi: 10.1111/nyas.13120. Epub 2016 Jul 6.

Analysis of γ-aminobutyric acid (GABA) type A receptor subtypes using isosteric and allosteric ligands.使用等排体和变构配体分析γ-氨基丁酸（GABA）A型受体亚型

Neurochem Res. 2014 Oct;39(10):1924-41. doi: 10.1007/s11064-014-1382-3. Epub 2014 Jul 12.

GABAA receptor target of tetramethylenedisulfotetramine.四亚甲基二砜四胺的 GABA A 受体靶标。

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8607-12. doi: 10.1073/pnas.1407379111. Epub 2014 May 27.

Differential antagonism of tetramethylenedisulfotetramine-induced seizures by agents acting at NMDA and GABA(A) receptors.四亚甲基二砜四胺诱导的惊厥的 NMDA 和 GABA(A) 受体作用药物的差异拮抗作用。

Toxicol Appl Pharmacol. 2012 Nov 15;265(1):113-21. doi: 10.1016/j.taap.2012.08.037. Epub 2012 Sep 27.

Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation.四亚甲基二砜四胺改变培养海马神经元中的 Ca²⁺动力学：NMDA 受体阻断和 GABA(A)受体正性调节的缓解作用。

Toxicol Sci. 2012 Dec;130(2):362-72. doi: 10.1093/toxsci/kfs244. Epub 2012 Aug 13.

Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine.急性和重复接触四亚甲基二砜四胺诱导的惊厥特征。

J Pharmacol Exp Ther. 2012 May;341(2):435-46. doi: 10.1124/jpet.111.190579. Epub 2012 Feb 10.

Teratogenesis of polychlorocycloalkane insecticides in chicken embryos resulting from their interactions at the convulsant recognition sites of the GABA (pro)receptor complex.

Bull Environ Contam Toxicol. 1989 May;42(5):707-15. doi: 10.1007/BF01700392.

Differential effects of gamma-hexachlorocyclohexane (lindane) on pharmacologically-induced seizures.

Arch Toxicol. 1987 Apr;59(6):397-401. doi: 10.1007/BF00316204.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验