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迟发性皮肤卟啉症患者T细胞、B细胞及携带血红素结合蛋白淋巴细胞的研究(作者译)

[Investigations of the T and B cells and the hemopexin-carrying lymphocytes in cases of porphyria cutanea tarda (author's transl)].

作者信息

Simon N, Husz S, Dobozy A, Hunyadi J

出版信息

Arch Dermatol Res (1975). 1976 Apr 21;255(2):149-56. doi: 10.1007/BF00558522.

Abstract

The immunoglobulins and hemopexin carrying cells have been determined in 14 patients having Porphyria cutanea tarda and in 15 healthy volunteers. At the same time, the stimulating effect of phytohemaglutinine and the leucocytesmigration inhibition by purified tuberculine proteins, were measured. In the 14 cases of Porphyria cutanea tarda, the IgG content and the number of hemopexin carrying lymphocytes was significantly increased, while the amounts of the other immunoglobuline carrying cells, and of T lymphocytes, was unchanged. Phytohemaglutinine stimulation and inhibition of leukocytes migration by purified tuberculine proteins were found to be identical in both patients and control groups.

摘要

对14例迟发性皮肤卟啉病患者和15名健康志愿者的携带免疫球蛋白和血红素结合蛋白的细胞进行了测定。同时,测量了植物血凝素的刺激作用以及纯化结核菌素蛋白对白细胞迁移的抑制作用。在14例迟发性皮肤卟啉病患者中,携带IgG的细胞和携带血红素结合蛋白的淋巴细胞数量显著增加,而携带其他免疫球蛋白的细胞数量以及T淋巴细胞数量未发生变化。结果发现,患者组和对照组中植物血凝素刺激和纯化结核菌素蛋白对白细胞迁移的抑制作用是相同的。

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