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[动态血压监测的作用与局限性]

[The usefulness and limits of the ambulatory monitoring of arterial pressure].

作者信息

Crippa G

机构信息

Dipartimento di Medicina Interna, Ospedale Civile di Piacenza.

出版信息

Ann Ital Med Int. 2000 Jan-Mar;15(1):63-9.

Abstract

The interpretation of blood pressure values, measured by the physician in the medical environment, has some limitations. Blood pressure fluctuates considerably due to circadian rhythm and various environmental stimuli and thus casual readings may not be representative of the true blood pressure status of the patient. Non-invasive ambulatory blood pressure monitoring has greatly increased our knowledge regarding the diagnosis, treatment efficacy, natural history and even prognosis of hypertension. This technique allows the evaluation of repeated blood pressure measurements at given times (daytime, nighttime, early-morning) and in different conditions (awake, asleep, at rest, during physical or mental activity etc.). Many studies have shown that the whole-day values obtained with such devices correlate better with the morbidity and mortality associated with hypertension than does casual office blood pressure. The 24-hour blood pressure recording is useful in the diagnosis of hypertension, particularly to discriminate so called white coat hypertension (for which the term isolated clinic hypertension has recently been proposed). Ambulatory blood pressure monitoring provides reliable and detailed information on the efficacy of pharmacological treatment and its ability to cover the whole day. These considerations notwithstanding, the application of this technique is still far from routine in the clinical management of arterial hypertension. Its major limit is that the normalcy of ambulatory blood pressure values still remains to be calculated, and only hypothetical normal reference values, derived from studies of selected normotensive populations, are presently available.

摘要

医生在医疗环境中测量的血压值的解读存在一些局限性。由于昼夜节律和各种环境刺激,血压会有很大波动,因此偶尔的读数可能无法代表患者的真实血压状况。无创动态血压监测极大地增加了我们对高血压的诊断、治疗效果、自然病程甚至预后的了解。这项技术可以在特定时间(白天、夜间、清晨)和不同条件下(清醒、睡眠、休息、身体或精神活动期间等)评估重复的血压测量值。许多研究表明,使用此类设备获得的全天血压值与高血压相关的发病率和死亡率的相关性比偶尔的诊室血压更好。24小时血压记录在高血压诊断中很有用,特别是用于鉴别所谓的白大衣高血压(最近有人提出用孤立性诊室高血压这一术语)。动态血压监测提供了关于药物治疗效果及其覆盖全天能力的可靠而详细的信息。尽管有这些考虑因素,但在动脉高血压的临床管理中,这项技术的应用仍远未成为常规。其主要局限性在于动态血压值的正常范围仍有待计算,目前只有从选定的血压正常人群的研究中得出的假设性正常参考值。

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