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脑刺伤中CD44表达的诱导:CD44表达的长期持续存在。

Induction of CD44 expression in stab wounds of the brain: long term persistence of CD44 expression.

作者信息

Stylli S S, Kaye A H, Novak U

机构信息

Department of Neurosurgery, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.

出版信息

J Clin Neurosci. 2000 Mar;7(2):137-40. doi: 10.1054/jocn.1999.0187.

DOI:10.1054/jocn.1999.0187
PMID:10844800
Abstract

We studied the expression of the hyaluronan receptor protein CD44 in the mouse brain in response to stab injuries. CD44 expression was strongly activated in the area surrounding the injury within 2 days and then persisted for over 2 months. The expression extended in a direct line the depth of the actual wound inflicted. It appears that CD44 may be involved in the wound healing processes following injury to the brain.

摘要

我们研究了透明质酸受体蛋白CD44在小鼠脑中对刺伤的反应表达。CD44表达在损伤后2天内在损伤周围区域被强烈激活,然后持续超过2个月。其表达沿实际造成的伤口深度呈直线扩展。看来CD44可能参与脑损伤后的伤口愈合过程。

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