Stylli S S, Kaye A H, Novak U
Department of Neurosurgery, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.
J Clin Neurosci. 2000 Mar;7(2):137-40. doi: 10.1054/jocn.1999.0187.
We studied the expression of the hyaluronan receptor protein CD44 in the mouse brain in response to stab injuries. CD44 expression was strongly activated in the area surrounding the injury within 2 days and then persisted for over 2 months. The expression extended in a direct line the depth of the actual wound inflicted. It appears that CD44 may be involved in the wound healing processes following injury to the brain.
我们研究了透明质酸受体蛋白CD44在小鼠脑中对刺伤的反应表达。CD44表达在损伤后2天内在损伤周围区域被强烈激活,然后持续超过2个月。其表达沿实际造成的伤口深度呈直线扩展。看来CD44可能参与脑损伤后的伤口愈合过程。