Biro P, Layer M, Wiedemann K, Seifert B, Spahn D R
Institute of Anaesthesiology, University Hospital Zurich, Switzerland.
Br J Anaesth. 2000 May;84(5):635-7. doi: 10.1093/bja/84.5.635.
Oxygen saturation and carbon dioxide values should be monitored during high-frequency jet ventilation (HFJV). Modern transcutaneous PCO2 (PtcCO2) measurement allows the estimation of ventilation efficiency. We studied how tests of lung function could predict carbon dioxide elimination during HFJV. Lung function tests from 180 adult patients undergoing rigid bronchoscopy were analysed as factors affecting carbon dioxide elimination. The lung function test results showed a significant relationship with the efficiency of carbon dioxide elimination; the greatest impairment of carbon dioxide elimination was found in patients with combined abnormalities of lung function. Further factors associated with difficult carbon dioxide elimination were male gender and elevated body weight. Of the patients investigated, 72% had normal carbon dioxide elimination, whereas in 23% hypercapnia could be avoided only by increasing the driving pressure. The prevalence of abnormal preoperative lung function test results predicts (sensitivity 76%, positive predictive value 27%) impaired carbon dioxide elimination during jet ventilation and rigid bronchoscopy.
在高频喷射通气(HFJV)期间,应监测血氧饱和度和二氧化碳值。现代经皮二氧化碳(PtcCO2)测量可用于评估通气效率。我们研究了肺功能测试如何预测HFJV期间的二氧化碳清除情况。对180例接受硬质支气管镜检查的成年患者的肺功能测试结果进行分析,将其作为影响二氧化碳清除的因素。肺功能测试结果与二氧化碳清除效率显著相关;肺功能合并异常的患者二氧化碳清除受损最为严重。与二氧化碳清除困难相关的其他因素包括男性性别和体重增加。在接受调查的患者中,72%的患者二氧化碳清除正常,而23%的患者只有通过增加驱动压力才能避免高碳酸血症。术前肺功能测试结果异常的患病率可预测(敏感性76%,阳性预测值27%)喷射通气和硬质支气管镜检查期间二氧化碳清除受损情况。