Biros D J, Gelatt K N, Brooks D E, Kubilis P S, Andrew S E, Strubbe D T, Whigham H M
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610, USA.
J Am Vet Med Assoc. 2000 Jun 1;216(11):1780-6. doi: 10.2460/javma.2000.216.1780.
To examine postoperative ocular hypertension (POH) and other variables as predictors of the risk of developing glaucoma after cataract surgery in dogs.
Retrospective study.
220 dogs that had cataract surgery.
Medical records of 220 dogs (346 eyes) that had extracapsular cataract removal or phacoemulsification of cataracts were reviewed. With respect to glaucoma development, 8 variables were analyzed, which included development of POH, breed, sex, age at time of surgery, eye (right vs left), phacoemulsification time, intraocular lens (IOL) placement (yes or no), and stage of cataract development. Eyes developed glaucoma within 6 or 12 months of surgery or did not have signs of glaucoma at least 6 or 12 months after cataract surgery.
Of 346 eyes, 58 (16.8%) developed glaucoma after surgery. At 6 months, 32 of 206 (15.5%) eyes examined had glaucoma; at 12 months, 44 of 153 (28.8%) eyes examined had glaucoma. Median follow-up time was 5.8 months (range, 0.1 to 48 months). Mixed-breed dogs were at a significantly lower risk for glaucoma, compared with other breeds. Eyes with IOL placement were at a significantly lower risk for glaucoma, compared with eyes without IOL placement. Eyes with hypermature cataracts were at a significantly higher risk for glaucoma, compared with eyes with mature or immature cataracts.
Multiple factors appear to contribute to the onset of glaucoma in dogs after cataract surgery. Complications prohibiting IOL placement during cataract surgery may lead to a high risk of glaucoma development.
研究术后高眼压(POH)及其他变量作为犬白内障手术后发生青光眼风险的预测指标。
回顾性研究。
220只接受白内障手术的犬。
回顾了220只犬(346只眼)行白内障囊外摘除术或超声乳化白内障吸除术的病历。关于青光眼的发生,分析了8个变量,包括POH的发生、品种、性别、手术时年龄、眼别(右眼与左眼)、超声乳化时间、人工晶状体(IOL)植入情况(有或无)以及白内障发展阶段。观察眼在手术后6个月或12个月内发生青光眼,或在白内障手术后至少6个月或12个月无青光眼体征。
346只眼中,58只(16.8%)术后发生青光眼。术后6个月,206只受检眼中32只(15.5%)发生青光眼;术后12个月,153只受检眼中44只(28.8%)发生青光眼。中位随访时间为5.8个月(范围0.1至48个月)。与其他品种相比,混种犬发生青光眼的风险显著较低。与未植入IOL的眼相比,植入IOL的眼发生青光眼的风险显著较低。与成熟或未成熟白内障的眼相比,过熟期白内障的眼发生青光眼的风险显著较高。
多种因素似乎与犬白内障手术后青光眼的发生有关。白内障手术期间禁止植入IOL的并发症可能导致青光眼发生的高风险。