Masland R H, Raviola E
Howard Hughes Medical Institute, Massachusetts General Hospital, Boston 02114, USA.
Annu Rev Neurosci. 2000;23:249-84. doi: 10.1146/annurev.neuro.23.1.249.
The mammalian retina contains upward of 50 distinct functional elements, each carrying out a specific task. Such diversity is not rare in the central nervous system, but the retina is privileged because its physical location, the distinctive morphology of its neurons, the regularity of its architecture, and the accessibility of its inputs and outputs permit a unique variety of experiments. Recent strategies for confronting the retina's complexity attempt to marry genetic approaches to new kinds of anatomical and electrophysiological techniques.
哺乳动物的视网膜包含50多种不同的功能元件,每个元件都执行一项特定任务。这种多样性在中枢神经系统中并不罕见,但视网膜具有特殊优势,因为其物理位置、神经元独特的形态、结构的规律性以及输入和输出的可及性允许进行各种各样独特的实验。最近应对视网膜复杂性的策略试图将遗传学方法与新型解剖学和电生理学技术相结合。