deCharms R C, Zador A
Keck Center for Integrative Neuroscience, University of California, San Francisco 94143-0732, USA.
Annu Rev Neurosci. 2000;23:613-47. doi: 10.1146/annurev.neuro.23.1.613.
The principle function of the central nervous system is to represent and transform information and thereby mediate appropriate decisions and behaviors. The cerebral cortex is one of the primary seats of the internal representations maintained and used in perception, memory, decision making, motor control, and subjective experience, but the basic coding scheme by which this information is carried and transformed by neurons is not yet fully understood. This article defines and reviews how information is represented in the firing rates and temporal patterns of populations of cortical neurons, with a particular emphasis on how this information mediates behavior and experience.
中枢神经系统的主要功能是表征和转换信息,从而介导适当的决策和行为。大脑皮层是在感知、记忆、决策、运动控制和主观体验中维持和使用的内部表征的主要场所之一,但神经元携带和转换这些信息的基本编码方案尚未完全被理解。本文定义并综述了信息如何在皮层神经元群体的放电率和时间模式中得到表征,特别强调了这些信息如何介导行为和体验。