Lydaki E, Bolonaki I, Stiakaki E, Kambourakis A, Cordeiro P B, Meyers P A, Delides G, Hatzimanolis P, Kalmanti M
Department of Pediatric Hematology/Oncology, University Hospital of Heraklion, Crete, Greece.
Pediatr Hematol Oncol. 2000 Jun;17(4):335-40. doi: 10.1080/088800100276334.
Mandibular osteogenic sarcoma (OS) is a very rare entity in childhood. Adequate surgical rejection with a wide margin of normal tissue is the mainstay of treatment of this site, while the role of adjuvant chemotherapy remains uncertain. A case is presented of a 15 1/2-year-old male with a huge OS of the mandible. The boy underwent surgical resection of the mandible with immediate fibula free flap reconstruction and is alive and free of disease 6 1/2 years following unitial diagnosis. This case suggests that immediate bone reconstitution with vascularized grafts have good functional and morphological results for osteosarcoma of the lower jaw.
下颌骨骨肉瘤在儿童时期非常罕见。对该部位进行足够的手术切除并保留较宽的正常组织切缘是主要治疗方法，而辅助化疗的作用仍不明确。本文报告一例15岁半男性下颌骨巨大骨肉瘤病例。该男孩接受了下颌骨手术切除并立即行游离腓骨瓣重建，初次诊断6年半后仍存活且无疾病复发。该病例表明，采用带血管移植物立即进行骨重建对下颌骨骨肉瘤具有良好的功能和形态学效果。
