Brauner E, Quarato A, De Angelis F, Pompa G, Jamshir S, Valentini V, Di Carlo S
D.D.S.,Università degli studi di Roma La Sapienza.
D.D.S., Università degli studi di Roma La Sapienza.
Clin Ter. 2017 Nov-Dec;168(6):e392-e396. doi: 10.7417/T.2017.2040.
Osteosarcoma is an aggressive primary bone tumor composed of connective tissue cells directly producing osteoid and bone. Prosthetic rehabilitations in post-oncological patients after bone reconstruction are not substantially different than those of patients affected by severe atrophy of upper or lower jaw after bone reconstruction. The treatment for patients with a malignant neoplasia of the oral cavity requires multidisciplinary approach by a team of different specialists that follow the patient through the phases of diagnosis, therapy and oral rehabilitation. Reconstructive surgery of jaws using vascularized free flap allows a significant gain of tissues that enables a successful final prosthetic rehabilitation. In fact main prosthetics difficulties result from lack of hard and soft tissues in affected area. Reconstructed patients have a greater ease of care management.
A 25-year-old Caucasian male was diagnosed with chondroblastic osteosarcoma of the pre-maxilla. The patient initially noticed the displacement of his maxillary incisors with progression into a definite swelling of the pre-maxillary a month later. Computerized Tomographic Scan and Radionuclide Bone Scan revealed the absence of both distant metastasis and regional nodal involvement. A biopsy and subsequent histopathology examination confirmed the lesion as being a chondroblastic type of osteosarcoma. The case study directed us to rehabilitate the patient by implant supported prosthesis consisting 3 different components: a titanium base screwed on implants, a titanium structure (primary structure) assembled on the base and a composite coatedstructure (secondary structure) that reproduced teeth and gum. At surgery, we proceeded placing 6 dental implants in 1.4, 1.3 1.2, 2.1, 2.2 and 2.4 positions. Contextually was performed a bone graft using particulate bone and collagen membranes.
Prosthetic rehabilitation in Maxillofacial Osteosarcoma treatment is an hard challenge for prosthodontist due to anatomic conditions of this kind of patients. Dental implants play a crucialrole in the therapy of patients affected by malignancies in the head-and-neck region. The goal of implant rehabilitationis to improve the quality of life of these patients by allowing proper retention of removable prostheses and a reduction in the load placed on vulnerable soft tissues. Today prosthetically guided rehabilitation represents the main rehabilitation protocol in prosthodontics, especially in those oncological patients with relevant lost of tissues and modified anatomy.
骨肉瘤是一种侵袭性原发性骨肿瘤,由直接产生类骨质和骨的结缔组织细胞组成。肿瘤患者骨重建后的修复性康复与上下颌骨严重萎缩患者骨重建后的修复性康复并无实质性差异。口腔恶性肿瘤患者的治疗需要由不同专科医生组成的团队采用多学科方法,在诊断、治疗和口腔康复阶段对患者进行跟踪。使用带血管游离皮瓣进行颌骨重建手术可显著增加组织量,从而实现成功的最终修复性康复。事实上,主要的修复困难源于患区软硬组织的缺失。接受重建手术的患者在护理管理上更加轻松。
一名25岁的白种男性被诊断为上颌前部软骨母细胞性骨肉瘤。患者最初注意到上颌切牙移位,一个月后发展为上颌前部明显肿胀。计算机断层扫描和放射性核素骨扫描显示无远处转移和区域淋巴结受累。活检及随后的组织病理学检查证实病变为软骨母细胞型骨肉瘤。该病例研究指导我们通过由三种不同部件组成的种植体支持假体为患者进行康复治疗:拧在种植体上的钛基台、安装在基台上的钛结构(主结构)以及复制牙齿和牙龈的复合涂层结构(次结构)。手术时,我们在1.4、1.3、1.2、2.1、2.2和2.4位置植入了6颗牙种植体。同时,使用颗粒骨和胶原膜进行了骨移植。
由于这类患者的解剖条件,颌面骨肉瘤治疗中的修复性康复对口腔修复医生来说是一项艰巨的挑战。牙种植体在头颈部恶性肿瘤患者的治疗中起着关键作用。种植体康复治疗的目标是通过使可摘义齿获得适当固位并减轻对脆弱软组织的负荷,来提高这些患者的生活质量。如今,修复引导康复是口腔修复学中的主要康复方案,尤其是在那些组织大量缺失且解剖结构改变了的肿瘤患者中。