Koch K M, Bechstein P B, Fassbinder W, Kaltwasser P, Schoeppe W, Werner E
Proc Eur Dial Transplant Assoc. 1976;12:362-9.
In 38 patients with chronic renal failure total daily blood loss and intestinal iron absorption were determined by means of a whole-body counter and radioiron. Bone marrow iron content was measured histochemically. Mean daily blood loss (corrected for laboratory blood sampling) and iron absorption were significantly higher than in normal controls. Bone marrow iron content was reduced in 46% of the patients. The results prove that gastrointestinal blood loss in patients with chronic renal failure is of such magnitude that negative iron balance results.
对38例慢性肾功能衰竭患者,采用全身计数器和放射性铁测定每日总失血量和肠道铁吸收量。采用组织化学方法测定骨髓铁含量。(校正实验室采血因素后的)平均每日失血量和铁吸收量显著高于正常对照组。46%的患者骨髓铁含量降低。结果证明,慢性肾功能衰竭患者胃肠道失血量之大足以导致铁负平衡。