Appleton R, Beirne M, Acomb B
Roald Dahl EEG Department, Alder Hey Children's Hospital, Liverpool, UK.
Seizure. 2000 Mar;9(2):108-11. doi: 10.1053/seiz.1999.0376.
Photosensitivity is reported to occur in approximately 40% of patients with juvenile myoclonic epilepsy. Our experience suggests that the prevalence is higher and may be related to both the duration of intermittent photic stimulation and also the age at which the procedure is undertaken. A two-year retrospective review of all EEGs was undertaken on all children attending a paediatric EEG department to identify those with juvenile myoclonic epilepsy. Photosensitivity was defined as a generalized spike or spike-wave paroxysm occurring at least twice during intermittent photic stimulation. Sixty-one children with a diagnosis of juvenile myoclonic epilepsy with a median age of 13 (range 7-16) years were identified, 55 (90%) of whom were photosensitive. Eighteen of these 55 patients showed photosensitivity only after four minutes of continuous photic stimulation. The prevalence of photosensitivity in juvenile myoclonic epilepsy is likely to be higher than previously reported. When a diagnosis of juvenile myoclonic epilepsy is being considered, the initial diagnostic EEG should include intermittent photic stimulation for up to five minutes, or less if the patient shows evidence of photosensitivity. The identification of photosensitivity may have important management implications.
据报道，青少年肌阵挛性癫痫患者中约40%会出现光敏性。我们的经验表明，其患病率更高，可能与间歇性光刺激的持续时间以及进行该检查时的年龄有关。对一家儿科脑电图科室的所有儿童进行了为期两年的脑电图回顾性研究，以确定患有青少年肌阵挛性癫痫者。光敏性定义为在间歇性光刺激期间至少出现两次的全身性棘波或棘慢波发作。共识别出61名诊断为青少年肌阵挛性癫痫的儿童，中位年龄为13岁（范围7 - 16岁），其中55名（90%）有光敏性。这55名患者中有18名仅在持续光刺激4分钟后才出现光敏性。青少年肌阵挛性癫痫中光敏性的患病率可能高于先前报道。当考虑诊断青少年肌阵挛性癫痫时，初始诊断性脑电图应包括长达5分钟的间歇性光刺激，如果患者出现光敏性证据则时间可缩短。光敏性的识别可能对治疗管理有重要意义。
