具有横纹肌样特征的子宫子宫内膜间质肉瘤

Endometrial stromal sarcoma of the uterus with rhabdoid features.

作者信息

Tanimoto A, Sasaguri T, Arima N, Hashimoto H, Hamada T, Sasaguri Y

机构信息

Department of Pathology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.

出版信息

Pathol Int. 1996 Mar;46(3):231-7. doi: 10.1111/j.1440-1827.1996.tb03604.x.

DOI:10.1111/j.1440-1827.1996.tb03604.x

PMID:10846576

Abstract

A case of endometrial stromal sarcoma of the uterus with rhabdoid features, occurring in a 57 year old woman is reported. Electron microscopy and immunohistochemistry revealed that the rhabdoid cells contained intermediate filaments which were positive for vimentin, cytokeratin, alpha-smooth muscle actin, and muscle specific actin, but not for myoglobin and desmin. This indicated that the tumor in this case differed somewhat from the three rhabdoid tumors and an endometrial stromal sarcoma with rhabdoid differentiation previously reported and that, therefore, these tumors were heterogeneous.

摘要

本文报告了一例发生于57岁女性的具有横纹肌样特征的子宫子宫内膜间质肉瘤。电子显微镜和免疫组织化学检查显示，横纹肌样细胞含有中间丝，波形蛋白、细胞角蛋白、α平滑肌肌动蛋白和肌肉特异性肌动蛋白呈阳性，但肌红蛋白和结蛋白呈阴性。这表明该病例中的肿瘤与先前报道的三种横纹肌样肿瘤以及具有横纹肌样分化的子宫内膜间质肉瘤有所不同，因此，这些肿瘤具有异质性。