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[与横纹肌样表型及“性索样”分化区域相关的子宫内膜间质肿瘤]

[Endometrial stromal tumor associated with rhabdoid phenotype and and zones of "sex cord-like" differentiation].

作者信息

Rosty C, Genestie C, Blondon J, Le Charpentier Y

机构信息

Service Central d'Anatomie et de Cytologie Pathologiques, Paris.

出版信息

Ann Pathol. 1998 Apr;18(2):133-6.

PMID:9608867
Abstract

An unusual endometrial stromal sarcoma is described in a 50-year-old patient. The distinctive feature of this case is the focal occurrence of sex cord-like pattern and rhabdoid appearance of tumor cells. Rhabdoid cells have an eosinophilic cytoplasm and a vesicular nucleus with a prominent nucleolus. Immunohistochemistry showed positive cytoplasmic staining for both cytokeratin and vimentin, and ultrastructural examination identified tumor cells with abundant cytoplasmic intermediate filaments. To our knowledge, only one case of endometrial stromal sarcoma with this unusual morphological association has been reported in the literature.

摘要

本文描述了一名50岁患者所患的一种罕见的子宫内膜间质肉瘤。该病例的独特特征是肿瘤细胞局灶性出现性索样模式和横纹肌样外观。横纹肌样细胞具有嗜酸性细胞质和一个带有明显核仁的泡状核。免疫组织化学显示细胞角蛋白和波形蛋白的细胞质染色均为阳性,超微结构检查发现肿瘤细胞含有丰富的细胞质中间丝。据我们所知,文献中仅报道过一例具有这种不寻常形态学关联的子宫内膜间质肉瘤病例。

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