Achiron R, Zimand S, Hegesh J, Lipitz S, Zalel Y, Rotstein Z
Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Ultrasound Obstet Gynecol. 2000 Mar;15(3):226-30. doi: 10.1046/j.1469-0705.2000.00068.x.
To establish in-utero reference ranges for fetal transverse aortic arch diameter (TAD) and distal aortic isthmus diameter (DAID) using high-resolution ultrasound techniques.
A prospective, cross-sectional study was performed on 125 normal singleton pregnancies between 14 and 38 weeks' gestation. Transverse and diameter and DAID were measured by transvaginal ultrasonography until 17 weeks' gestation, and by abdominal ultrasound between 18 and 38 weeks' gestation.
Transverse arch diameter as a function of gestational age was expressed by the regression equation TAD = -1.17 + 0.169 X GA, and DAID = -1.39 + 0.189 X GA; TAD and DAID are transverse aortic and distal aortic isthmus diameters expressed in millimeters and GA is gestational age in weeks. The correlation r = 0.924 and 0.938 was found to be highly statistically significant (P < 0.001) for TAD and DAID. The normal mean of TAD and DAID per week and the 95% prediction limits were also defined.
The normative data established by us may be helpful in the prenatal diagnosis of congenital heart defects, including abnormal growth of the aortic arch.
使用高分辨率超声技术建立胎儿横位主动脉弓直径（TAD）和主动脉峡部远端直径（DAID）的宫内参考范围。
对125例孕14至38周的正常单胎妊娠进行前瞻性横断面研究。妊娠17周前经阴道超声测量横径和DAID，妊娠18至38周经腹部超声测量。
横弓直径与孕周的函数关系由回归方程TAD = -1.17 + 0.169×GA表示，DAID = -1.39 + 0.189×GA；TAD和DAID分别为以毫米为单位的横位主动脉和主动脉峡部远端直径，GA为以周为单位的孕周。TAD和DAID的相关性r分别为0.924和0.938，具有高度统计学意义（P < 0.001）。还定义了每周TAD和DAID的正常均值及95%预测范围。
我们建立的规范数据可能有助于先天性心脏缺陷的产前诊断，包括主动脉弓异常生长。
