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对上颌窦使用Algipore进行骨增量术后六个月,人类骨样本的组织形态学发现。

Histomorphologic findings on human bone samples six months after bone augmentation of the maxillary sinus with Algipore.

作者信息

Schopper C, Moser D, Wanschitz F, Watzinger F, Lagogiannis G, Spassova E, Ewers R

机构信息

University Clinic of Oral and Maxillofacial Surgery, General Hospital, University of Vienna.

出版信息

J Long Term Eff Med Implants. 1999;9(3):203-13.

Abstract

Sinus grafting, a popular and standard treatment for maxillary atrophy, uses a variety of grafting materials. In this study, specimens obtained 6 months after sinus grafting with Algipore were evaluated under light microscopy and showed osseoformation, xenograft degradation, and bone ingrowth into particles. Osteoblastic cells were embedded in the intracorpuscular bone matrix, which indicated that xenograft particles are an osseoconductive scaffold and stimulate matrix deposition. Acute inflammatory responses after insertion of Algipore did not occur. Particles were degraded during physiologic bone remodeling, and newly formed bone gradually replaced resorbed biomaterial.

摘要

窦底提升术是治疗上颌骨萎缩的一种常用标准方法,使用多种移植材料。在本研究中,对使用藻酸盐多孔聚乙烯进行窦底提升术后6个月获取的标本进行光学显微镜评估,结果显示有骨形成、异种移植物降解以及骨长入颗粒中。成骨细胞包埋于细胞内骨基质中,这表明异种移植物颗粒是一种骨传导支架并能刺激基质沉积。植入藻酸盐多孔聚乙烯后未发生急性炎症反应。在生理性骨重塑过程中颗粒发生降解,新形成的骨逐渐替代吸收的生物材料。

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