Adelman J U, Mannix L K, Von Seggern R L
Headache Wellness Center, Greensboro, NC 27403, USA.
Headache. 2000 May;40(5):371-2. doi: 10.1046/j.1526-4610.2000.00055.x.
After taking both conventional oral rizatriptan tablets and oral disintegrating rizatriptan tablets in the treatment of migraine with or without aura, patients were permitted to select their formulation preference. All adult patients who had requested continuation of rizatriptan during a 6-month period were included in the study. Of the 367 patients studied, 188 selected the oral disintegrating tablet, while 179 preferred the conventional tablet. Although individual patients had strong preferences for one preparation over the other, no group preference was found.
在使用常规口服利扎曲普坦片和口腔崩解利扎曲普坦片治疗有或无先兆偏头痛后,允许患者选择他们偏爱的剂型。所有在6个月期间要求继续使用利扎曲普坦的成年患者均纳入研究。在研究的367例患者中,188例选择口腔崩解片,而179例更喜欢常规片剂。尽管个别患者对一种制剂的偏好明显高于另一种,但未发现群体偏好。