Carew D P, Bainbridge T
Lloydia. 1976 Mar-Jun;39(2-3):147-9.
Suspension cultures of Catharanthus roseus, Apocynum cannabinum and Conium maculatum were examined for their capacity to transform aniline, anisole, acetanilide, benzoic acid and coumarin. None of the cultures transformed acetanilide but each produced acetanilide when fed aniline. All three cultures converted benzoic acid to its para-hydroxy derivative. Coumarin was selectively hydroxylated at the 7-position by Catharanthus and Conium and anisole was O-demethylated only by older Catharanthus tissue.
对长春花、加拿大麻和毒参的悬浮培养物进行了检测,以考察它们转化苯胺、苯甲醚、乙酰苯胺、苯甲酸和香豆素的能力。没有一种培养物能转化乙酰苯胺,但在加入苯胺后,每种培养物都能产生乙酰苯胺。所有这三种培养物都能将苯甲酸转化为其对羟基衍生物。长春花和毒参能将香豆素选择性地在7位羟基化,而只有较老的长春花组织能使苯甲醚发生O-去甲基化反应。