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患有局限性回肠炎的猪的血液和血清的血液学及生化分析,特别涉及发病机制。

Hematological and biochemical analyses of blood and serum in pigs with regional ileitis with special reference to the pathogenesis.

作者信息

Martinsson K, Ekman L, Jönsson L

出版信息

Acta Vet Scand. 1976;17(2):233-43. doi: 10.1186/BF03547931.

Abstract

Biochemical and hematological analyses of blood and serum were performed in pigs with regional ileitis and in wasting pigs with a negative necropsy. In sera from pigs with regional ileitis the levels of total protein, albumin, transferrin, alkaline phosphatase and zinc were significantly decreased compared with normal pigs of the same age. The number of white blood cells, and the concentration of Cortisol and α-antitrypsin were significantly increased. In wasting pigs with early signs of regional ileitis or with a negative necropsy the same blood changes were observed but to a less degree. It was concluded that a wasting syndrome after weaning may precede regional ileitis. Concerning the etiology of regional ileitis the significance of malabsorption and wasting syndrome in combination with invasion of intestinal intercellular microorganisms is discussed.

摘要

对患有局限性回肠炎的猪以及尸检呈阴性的消瘦猪进行了血液和血清的生化及血液学分析。与同龄正常猪相比,患有局限性回肠炎的猪血清中总蛋白、白蛋白、转铁蛋白、碱性磷酸酶和锌的水平显著降低。白细胞数量、皮质醇和α-抗胰蛋白酶的浓度显著升高。在有局限性回肠炎早期迹象或尸检呈阴性的消瘦猪中,观察到了相同的血液变化,但程度较轻。得出的结论是,断奶后的消瘦综合征可能先于局限性回肠炎出现。关于局限性回肠炎的病因,讨论了吸收不良和消瘦综合征与肠道细胞间微生物入侵相结合的意义。

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