Harke H
Anaesthesist. 1976 Aug;25(8):374-9.
Microembolism is still a feared complication during and after blood transfusions. Up to now they could only be diminished by special filter systems. In spite of much research it has not been possible as yet to fine adequate remedies for the preservation of blood cells and for the decrease of aggregation in stored blood. As foregoing studies have shown the inhibition of aggregation is combined with a considerable impairment or even loss of platelet function. In these clinical experiments, however, it has been shown, that aggregations in stored blood are significantly stunted by early addition of Aprotinin. It is clinically important, that no inhibition of platelet function occured.
微栓塞仍是输血过程中和输血后令人担忧的并发症。到目前为止，只能通过特殊的过滤系统来减少微栓塞。尽管进行了大量研究，但尚未找到保存血细胞和减少库存血中聚集的适当补救措施。如先前的研究所示，抑制聚集与血小板功能的显著损害甚至丧失有关。然而，在这些临床实验中已经表明，通过早期添加抑肽酶，库存血中的聚集会显著受到抑制。临床上重要的是，血小板功能没有受到抑制。
