Gibson D T, Parales R E
Department of Microbiology, The Center for Biocatalysis and Bioprocessing, The University of lowa, lowa City, IA 52242, USA.
Curr Opin Biotechnol. 2000 Jun;11(3):236-43. doi: 10.1016/s0958-1669(00)00090-2.
Aromatic hydrocarbon dioxygenases belong to a large family of Rieske non-heme iron oxygenases. The dioxygenases have a broad substrate specificity and catalyze enantiospecific reactions with a wide range of substrates. These characteristics make them attractive synthons for the production of industrially and medically important chiral chemicals and also provide essential information for the development of bioremediation technology.
芳烃双加氧酶属于 Rieske 非血红素铁氧合酶的一个大家族。这些双加氧酶具有广泛的底物特异性,能催化多种底物的对映体特异性反应。这些特性使其成为生产工业和医学上重要手性化学品的有吸引力的合成子,也为生物修复技术的发展提供了重要信息。