El Samak Manar, Lotfy Hasnaa, Sedeek Abdelrahman M, Mohamed Yehia S, Solyman Samar M
Department of Microbiology & Immunology, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Department of Microbiology & Immunology, Faculty of Pharmacy, Sinai University-Elkantara Branches, Ismailia 41522, Egypt.
Microorganisms. 2025 Aug 9;13(8):1866. doi: 10.3390/microorganisms13081866.
() is a coagulase-negative species primarily associated with the degradation of organic matter, contributing to nutrient cycling in natural environments. This species has been mainly studied in clinical and terrestrial contexts, with no previous reports of its presence in marine environments. In this study, we report the first isolation of from a marine habitat. The strain SC-M1C was isolated from the Red Sea sponge . Whole-genome sequencing confirmed its taxonomic identity as . The genome uncovers potential adaptive characteristics that facilitate survival in marine ecosystems, comprising genes associated with osmoregulation, nutrient acquisition, stress response, and resistance to heavy metals. Moreover, multiple genomic islands and plasmids were identified, suggesting a potential role in horizontal gene transfer and environmental adaptability. The presence of biosynthetic gene clusters linked to non-ribosomal peptides, siderophores, and terpene production indicates potential for biochemical versatility beyond traditional metabolic expectations. This study presents the first genomic insights into in a marine context, highlighting its ecological significance and adaptive mechanisms in a high-salinity environment. These findings expand our understanding of staphylococcal ecology beyond terrestrial and clinical origins and provide a foundation for exploring the role of in marine microbial interactions and environmental resilience.
（）是一种凝固酶阴性菌种，主要与有机物降解相关，有助于自然环境中的养分循环。该菌种主要在临床和陆地环境中得到研究，此前尚无其在海洋环境中存在的报道。在本研究中，我们报告了首次从海洋栖息地分离出（）。菌株SC-M1C是从红海海绵（）中分离得到的。全基因组测序证实其分类学身份为（）。该基因组揭示了有助于在海洋生态系统中生存的潜在适应性特征，包括与渗透调节、养分获取、应激反应和重金属抗性相关的基因。此外，还鉴定出多个基因组岛和质粒，表明其在水平基因转移和环境适应性方面可能发挥的作用。与非核糖体肽、铁载体和萜类化合物生产相关的生物合成基因簇的存在表明，其生化多样性超出了传统代谢预期。本研究首次在海洋环境中对（）进行了基因组学研究，突出了其在高盐环境中的生态意义和适应性机制。这些发现扩展了我们对葡萄球菌生态学的理解，超越了陆地和临床来源，并为探索（）在海洋微生物相互作用和环境恢复力中的作用奠定了基础。
