Havran W L
Department of Immunology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Immunol Res. 2000;21(2-3):63-9. doi: 10.1385/IR:21:2-3:63.
My colleagues and I have a long-term interest in interactions between intraepithelial gammadelta T cells and neighboring epithelial cells. We have focused our studies on interactions in the thymus, skin, and intestine, and are investigating the development, specificity, and function of these gammadelta T cells. Our results have defined unique properties of these cells and support a specialized role for epithelial gammadelta T cells in immune surveillance, wound repair, inflammation, and protection from malignancy.
我和我的同事长期关注上皮内γδT细胞与邻近上皮细胞之间的相互作用。我们将研究重点集中在胸腺、皮肤和肠道中的相互作用，并正在研究这些γδT细胞的发育、特异性和功能。我们的研究结果明确了这些细胞的独特特性，并支持上皮γδT细胞在免疫监视、伤口修复、炎症以及预防恶性肿瘤方面发挥特殊作用。
