成年胸腺切除术后牛胸导管淋巴细胞对植物血凝素的体外反应。
In vitro response of bovine thoracic duct lymphocyte to phytohaemagglutinin following adult thymectomy.
作者信息
Sharbaugh R J, Ainsworth S K, Fitts C T
出版信息
Clin Exp Immunol. 1976 Aug;25(2):342-6.
The effect of adult thymectomy on the thoracic duct lymphocyte population of yearling calves has been investigated. Four to 6 weeks after thymectomy animals showed significantly reduced thoracic duct lymphocyte concentrations when compared to non-thymectomized controls. In addition, phytohaemagglutinin responsiveness of thoracic duct lymphocytes, measured by (3H) thymidine uptake, was significantly decreased following adult thymectomy. However, this decreased response to PHA was not accompanied by a change in spontaneous isotope incorporation. It is concluded that adult thymectomy in the bovine probably leads to a reduction in the number of PHA responsive T cells in the thoracic duct lymph.
已经研究了成年胸腺切除对一岁小牛胸导管淋巴细胞群的影响。与未进行胸腺切除的对照相比，胸腺切除动物在术后4至6周胸导管淋巴细胞浓度显著降低。此外，通过（3H）胸腺嘧啶核苷摄取测量，成年胸腺切除术后胸导管淋巴细胞对植物血凝素的反应性显著降低。然而，这种对PHA反应性的降低并未伴随自发同位素掺入的变化。得出的结论是，牛的成年胸腺切除可能导致胸导管淋巴中对PHA有反应的T细胞数量减少。
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