Friedlaender R P, Barile M F, Kuwabara T, Clark H F
Invest Ophthalmol. 1976 Aug;15(8):640-7.
The eye disease caused by SMCA may be best characterized as an endophthalmitis, with early retinitis followed by subsequent posterior uveitis. Pathologic features of lens included: proliferation and abnormal posterior extension of lens epithelium, increased accumulation of lens capsule material, and production of aberrant lens substance. Cataractous change appears to be secondary to intraocular inflammation. In addition to the above pattern, in roughly 20 per cent of all cases, 3 weeks after inoculation, lens capsule is destroyed giving rise to a foreign body granulomatous reaction.
由SMCA引起的眼部疾病最典型的特征可能是眼内炎，早期为视网膜炎，随后是后葡萄膜炎。晶状体的病理特征包括：晶状体上皮细胞增殖并向后异常延伸、晶状体囊膜物质积累增加以及异常晶状体物质的产生。白内障改变似乎是眼内炎症的继发结果。除上述模式外，在所有病例中约20%的情况下，接种后3周，晶状体囊膜被破坏，引发异物肉芽肿反应。
