Pouget J
Service de neurologie et maladies neuromusculaires, Hôpital de La Timone, Marseille.
Rev Prat. 2000 Apr 1;50(7):749-52.
Vasculitic neuropathy is an important cause of peripheral neuropathy because of its potentially severe prognosis and an early recommended therapy. Diagnosis is easy when the clinical presentation is an acute, painful, multiple mononeuropathy but more difficult when presenting as a polyneuropathy. Electrophysiologic studies play an important role in the diagnosis. Muscle and nerve biopsies confirm the vasculitic process and demonstrate ischemic neuropathy lesions. Polyarteritis nodosa, rheumatoid arthritis and non-systematic vasculitic neuropathy are the main conditions of vasculitic neuropathy. Usual treatment includes a combination of corticosteroids and cyclophosphamide.
血管炎性神经病是周围神经病的一个重要病因,因其预后可能严重且有早期推荐疗法。当临床表现为急性、疼痛性多发性单神经病时诊断容易,但表现为多发性神经病时则较难。电生理检查在诊断中起重要作用。肌肉和神经活检可证实血管炎过程并显示缺血性神经病病变。结节性多动脉炎、类风湿关节炎和非系统性血管炎性神经病是血管炎性神经病的主要类型。常用治疗包括皮质类固醇和环磷酰胺联合使用。