Non-electrostatic complexes with DNA: towards novel synthetic gene delivery systems.
作者信息
Soto J, Bessodes M, Pitard B, Mailhe P, Scherman D, Byk G
机构信息
UMR-7001 ENSCP/CNRS/Aventis Pharma Gencell, Vitry sur Seine, France.
出版信息
Bioorg Med Chem Lett. 2000 May 1;10(9):911-4. doi: 10.1016/s0960-894x(00)00118-9.
Abstract
We have developed new DNA complexing amphiphile based on Hoechst 33258 interaction with DNA grooves. The synthesis and physicochemical characterisation of lipid/DNA complexes, as compared to that of classical lipopolyamine for gene delivery, are described and discussed.
摘要
Zotero 插件