Leppäniemi A, Rich N, Pikoulis E, Rhee P, Burris D, Wherry D
Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Int Angiol. 2000 Mar;19(1):69-74.
Attempts to find alternatives to sutured vascular reconstruction techniques has continued for decades and include various forms of rings, tubes, endoluminal stents as well as gluing or welding techniques of large vessel anastomoses. One recently introduced technique uses nonpenetrating titanium clips for everted vessel approximation and closure. Experimental work on their use in various types of large vessel repairs and reconstructions has shown that the clips are easily applied with a short learning curve, create good conditions for vessel wall healing without causing excessive inflammation or fibrosis, and are considerably faster to apply when compared to standard suture techniques. Although there are some clinical reports of defective clipped closures causing postoperative bleeding complications, they are rare and most probably related to technical errors in applying the clips. The main disadvantages of the clips include the limited experience of their applicability in atherosclerotic vessels, lack of long term follow-up and cost. Potentially, the clips could be useful in the repair of multiple vascular injuries, in vessel repair or ligation performed in confined spaces, and in vascular procedures requiring the shortest possible cross-clamping time. Future applications could include endoscopic procedures as well as the use of a one-shot device which simultaneously applies up to a dozen clips to symmetrically everted and approximated vessel edges.
数十年来,人们一直在尝试寻找缝合血管重建技术的替代方法,这些方法包括各种形式的环、管、腔内支架以及大血管吻合的胶合或焊接技术。最近引入的一种技术是使用非穿透性钛夹进行外翻血管的贴合和闭合。关于其在各种类型大血管修复和重建中的应用的实验工作表明,这种夹子易于应用,学习曲线短,能为血管壁愈合创造良好条件,不会引起过度炎症或纤维化,而且与标准缝合技术相比,应用速度要快得多。尽管有一些临床报告称,夹闭闭合出现缺陷会导致术后出血并发症,但这种情况很少见,很可能与应用夹子时的技术失误有关。这些夹子的主要缺点包括在动脉粥样硬化血管中的应用经验有限、缺乏长期随访以及成本问题。潜在地,这些夹子可能在修复多处血管损伤、在狭窄空间进行的血管修复或结扎以及需要尽可能缩短交叉钳夹时间的血管手术中有用。未来的应用可能包括内窥镜手术以及使用一次性装置,该装置可同时将多达一打夹子应用于对称外翻并贴合的血管边缘。