Zlotnick C, Kohn R, Keitner G, Della Grotta S A
Butler Hospital/Brown University, Department of Psychiatry and Human Behaviour, 345 Blackstone Boulevard, Providence, RI 02906, USA.
J Affect Disord. 2000 Sep;59(3):205-15. doi: 10.1016/s0165-0327(99)00153-6.
The current study compared the quality of interpersonal relationships in individuals with major depressive disorder to individuals with dysthymia, comorbid depression, nonaffective disorders, and no psychiatric disorders.
Using data from the National Comorbidity Study, a series of logistic regressions, controlling for demographic variables, were conducted to examine the strength of the association between a major depressive disorder and interpersonal dysfunction (positive and negative interactions) in contrast to other psychiatric disorders.
Respondents with current major depressive disorder reported significantly fewer positive interactions and more negative interactions with their spouse or live-in partner than those with nonaffective disorders, and than those with no psychiatric disorders. There were no significant differences in quality of interpersonal relationships between respondents with major depressive disorder and those with dysthymia. Among those with major depressive disorder, comorbidity or treatment-seeking behavior did not significantly contribute to degree of interpersonal difficulties. The strength of the association between interpersonal dysfunction and depression were, in general, comparable for men and women with major depressive disorder.
The cross-sectional design of this report precludes inferences regarding causality between quality of interpersonal relationship and current major depressive disorder.
The results of this study indicate that, relative to psychiatric illness in general, poor intimate relationships are characteristic of a current major depressive disorder.
本研究比较了重度抑郁症患者与心境恶劣障碍患者、共病抑郁症患者、非情感性障碍患者及无精神障碍患者的人际关系质量。
利用全国共病调查的数据，进行了一系列逻辑回归分析，并对人口统计学变量进行了控制，以检验重度抑郁症与人际功能障碍（积极和消极互动）之间的关联强度，并与其他精神障碍进行对比。
与非情感性障碍患者及无精神障碍患者相比，当前患有重度抑郁症的受访者报告称，他们与配偶或同居伴侣的积极互动显著减少，消极互动显著增多。重度抑郁症患者与心境恶劣障碍患者的人际关系质量没有显著差异。在重度抑郁症患者中，共病或寻求治疗行为对人际困难程度没有显著影响。人际功能障碍与抑郁症之间的关联强度在患有重度抑郁症的男性和女性中总体相当。
本报告的横断面设计无法推断人际关系质量与当前重度抑郁症之间的因果关系。
本研究结果表明，相对于一般精神疾病而言，亲密关系不佳是当前重度抑郁症的一个特征。
