Osher Y, Mandel B, Shapiro E, Belmaker R H
Beer Sheva Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.
J Affect Disord. 2000 Sep;59(3):231-6. doi: 10.1016/s0165-0327(99)00148-2.
Previously published data show large differences between euthymic Israeli adult bipolar patients and US normative data on several measures of psychological functioning as assessed with a sensitive projective measure (Rorschach Inkblot Test). The current study examines the Rorschach performance of healthy offspring of bipolar parents and compares them to matched normal controls.
14 asymptomatic offspring of Israeli manic-depressive parents were matched for age, gender, and other demographic variables with 14 children of normal parents. All subjects were individually administered the Rorschach Inkblot Test, and protocols were scored blindly according to the Exner Comprehensive System.
Offspring of bipolar parents, like bipolar patients themselves, show significantly increased incidence and severity of thought disorder (as defined by Exner), lower numbers of cognitively mediated affective responses, and fewer responses indicating conventional perceptions.
Although the sample size is small, this study strengthens the possibility that these measures of psychological functioning may serve as markers for manic-depressive illness.
先前发表的数据显示，在使用一种敏感的投射测验（罗夏墨迹测验）评估的几种心理功能测量指标上，以色列处于心境正常期的成年双相情感障碍患者与美国的常模数据之间存在巨大差异。本研究考察双相情感障碍患者健康后代的罗夏测验表现，并将他们与匹配的正常对照组进行比较。
选取14名以色列躁郁症患者的无症状后代，在年龄、性别和其他人口统计学变量上与14名正常父母的子女进行匹配。所有受试者均单独接受罗夏墨迹测验，并根据艾克纳综合系统对测验记录进行盲评。
双相情感障碍患者的后代，与双相情感障碍患者本身一样，思维障碍的发生率和严重程度显著增加（如艾克纳所定义），认知介导的情感反应数量减少，表明传统认知的反应也减少。
尽管样本量较小，但本研究增强了以下可能性，即这些心理功能测量指标可能作为躁郁症的标志物。
