Kruse H, Eggers G, Mix E
Z Gesamte Inn Med. 1976 Jul 1;31(13):485-9.
On the basis of their ability of the spontaneous formation of rosettes by unsensibilised sheep erythrocytes the proportion of thymic lymphatic cells in 7 acute and 3 chronic lymphatic leukaemias was determined. Further observations on the content of T-cells in the peripheral blood were performed in leukoses, whereby the remission was begun with prednisone and cytostatics, under the immune stimulation with BCG during the remission and in 3 children with lymphogranulomatosis before and after splenectomy. The results of the acute stage of leucosis refer to the possibility of a prognostic evidence with the subclassification of the ALL. The T-cell-leukaemias revealed a particularly unfavourable course of disease. Cytochemically they were acute lymphatic leukaemias of undifferentiated type. In leucoses with smaller proportion of T-cells the blasts above all revealed a granular PAS-reaction.
根据未致敏绵羊红细胞自发形成玫瑰花结的能力，测定了7例急性和3例慢性淋巴细胞白血病中胸腺淋巴细胞的比例。对白血病患者外周血中T细胞含量进行了进一步观察，其中缓解期开始使用泼尼松和细胞抑制剂，缓解期接受卡介苗免疫刺激，以及3例淋巴肉芽肿病患儿在脾切除前后进行观察。白血病急性期的结果提示了对急性淋巴细胞白血病进行亚分类以提供预后证据的可能性。T细胞白血病显示出特别不利的病程。细胞化学检查显示它们是未分化型的急性淋巴细胞白血病。在T细胞比例较小的白血病中，原始细胞尤其显示出颗粒状PAS反应。
