Révész T, Szigeti R, Schuler D
Haematologia (Budap). 1975;9(1-2):35-8.
The capacity of leukaemic lymphoblasts and remission lymphocytes, obtained from 40 children with acute lymphoid leukaemia, to form sheep red blood cell rosettes was investigated. Lymphoblasts isolated from the peripheral blood of the patients prior to antileukaemic treatment showed greatly reduced numbers of rosette-forming cells as compared to controls (4.6% vs. 27.5%). The ratio of rosette-forming cells during intensive induction chemotherapy was still significantly lower than the control value (15.7%), while after the achievement of complete remission the number of RFC approximated the normal value (22.5%). The presence of leukaemic serum had no significant effect on the number of RFC.
对40名急性淋巴细胞白血病患儿的白血病淋巴母细胞和缓解期淋巴细胞形成绵羊红细胞花环的能力进行了研究。与对照组相比，在抗白血病治疗前从患者外周血中分离出的淋巴母细胞显示花环形成细胞数量大幅减少（4.6%对27.5%）。强化诱导化疗期间花环形成细胞的比例仍显著低于对照值（15.7%），而在完全缓解后，RFC数量接近正常值（22.5%）。白血病血清的存在对RFC数量没有显著影响。
