Kriuchyna Ie A
Lik Sprava. 2000 Mar(2):34-7.
Overall, thirty-two patients with acute pancreatitis (edematous, destructive, purulent forms) were studied for the state of lipid peroxidation (LPO), antioxidant defence (AOD), and trace element status. The development of destructive and purulent forms of acute pancreatitis was found out to be accompanied by activation of LPO processes, AOD breakdown, with profound disturbances having been disclosed in the metabolism of zinc, selenium, cuprum, manganum, that play an important part in LPO, AOD processes, and in those of immune defence. The secured results suggest that there is a need for us to include into a complex therapy of acute pancreatitis antioxidants and some trace elements (zinc, celenium) and that it is expedient to use indices for the LPO, AOD systems, and for trace element status in the differential diagnosis of clinical forms of acute pancreatitis, prognostication of development of purulent complications.
总体而言，对32例急性胰腺炎患者（水肿型、坏死型、化脓型）的脂质过氧化（LPO）状态、抗氧化防御（AOD）及微量元素状况进行了研究。结果发现，急性胰腺炎坏死型和化脓型的发展伴随着LPO过程的激活、AOD破坏，同时锌、硒、铜、锰代谢出现严重紊乱，这些元素在LPO、AOD过程以及免疫防御过程中发挥着重要作用。所得结果表明，有必要在急性胰腺炎的综合治疗中加入抗氧化剂和一些微量元素（锌、硒），并且在急性胰腺炎临床类型的鉴别诊断、化脓性并发症发展的预后判断中，使用LPO、AOD系统及微量元素状况的指标是适宜的。
