[The clinico-pathogenetic validation of rehabilitative-stage treatment in chronic pancreatitis].

A total of 252 patients were examined. It has been shown that forms of chronic pancreatitis (ChP) have some distinguishing features of the clinical course of the disease and depend on morphofunctional state of pancreas, its ecbolic activity, degree of microcirculatory disorders, state of lipid peroxidation (LPO), that of the antioxidant system of defence as well as psychophysiologic status of the personality, circadian and seasonal variability of functional activity of pancreas in patients with chronic pancreatitis. Substantiated in the paper is rehabilitative staged treatment of ChP patients, depending on ChP forms with due regard to the above-mentioned mechanisms of its relapse, most important of which is LPO status, that of antioxidant system of defence and microcirculation.