铊-201与镓-67成像在头颈部肿瘤评估中的比较。
Comparison of thallium-201 and gallium-67 imaging in evaluation of head and neck tumors.
作者信息
Tomura N, Hirano H, Watanabe O, Hirano Y, Kato K, Sasaki K, Watarai J
机构信息
Department of Radiology, Akita University School of Medicine, Akita City, Japan.
出版信息
J Comput Assist Tomogr. 2000 May-Jun;24(3):454-60. doi: 10.1097/00004728-200005000-00019.
PURPOSE
201Tl imaging was compared with 67Ga imaging in the detection of malignant head and neck tumors.
METHOD
Eighteen patients with tumors in the head and neck region underwent both planar and SPECT imaging using 201Tl-chloride and 67Ga-citrate. The detection of primary tumors and lymph node (LN) metastases by visual evaluation was compared between 201Tl and 67Ga imaging. Additionally, quantitative analysis of the SPECT images was performed in eight patients.
RESULTS
On visual evaluation, primary tumor uptake was detectable in 100% on the 201Tl SPECT images compared with 44% on the 67Ga SPECT images. The sensitivity, specificity, and accuracy of 201Tl in detecting LN metastases were higher than those of 67Ga SPECT; however, there was no statistical difference between 201Tl and 67Ga. The tumor-to-background ratio was significantly higher on 201Tl SPECT than on 67Ga SPECT.
CONCLUSION
This study suggested that 201Tl could be useful in the evaluation of malignant tumors in the head and neck region.
目的
比较201铊成像与67镓成像在检测头颈部恶性肿瘤中的应用。
方法
18名头颈部肿瘤患者接受了使用氯化201铊和枸橼酸67镓的平面及SPECT成像。比较了201铊成像与67镓成像通过视觉评估检测原发性肿瘤和淋巴结转移的情况。此外，对8名患者的SPECT图像进行了定量分析。
结果
在视觉评估中，201铊SPECT图像上原发性肿瘤摄取的可检测率为100%，而67镓SPECT图像上为44%。201铊检测淋巴结转移的敏感性、特异性和准确性高于67镓SPECT；然而，201铊与67镓之间无统计学差异。201铊SPECT上的肿瘤与背景比值显著高于67镓SPECT。
结论
本研究表明，201铊可用于评估头颈部区域的恶性肿瘤。
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