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乳内动脉-冠状动脉移植血管的通畅情况。

Patency of internal mammary-coronary grafts.

作者信息

Barner H B, Mudd J G, Mark A L, Ahmad N, Dickens J F

出版信息

Circulation. 1976 Dec;54(6 Suppl):III70-3.

PMID:1086746
Abstract

Patency of internal mammary artery (IMA) coronary grafts was evaluated in 150 patients having an early (20 days) and late (13 months) postoperative angiogram. Early and late failure for 76 right IMA grafts was 3 and 5 respectively and for 139 left IMA grafts 7 and 7 an overall IMA patency of 95% and 90%. The IMA and coronary internal diameter did not relate to graft closure. Right IMA free flow did not correlate with graft closure. Free flow for thrombosed left IMA grafts (91 ml/min) was significantly (P less than 0.05) lower than for patent grafts (118 ml/min). Right IMA anastomotic flow of 55 ml/min was significantly (P less than 0.001) higher than occluded graft flow of 26 ml/min as was true for patent left IMA grafts (55 ml/min) and occluded grafts (43 ml/min) (P less than 0.025). Five of 215 IMA grafts had diffuse stenosis (greater than 50%). Saphenous vein coronary bypass was performed in 88 instances with an early patency of 89% (79/88) and a late patency of 88% (78/88). Only one of 38 vein grafts to the right coronary artery failed whereas eight of 44 grafts to the circumflex artery occluded. Experience was associated with increased late IMA patency from 81% (57/70), to 89% (;8/76), to 99% (68/69) in each successive group of 50 patients. Currently, the left IMA is routinely used for the left anterior descending artery and the right IMA is rarely used.

摘要

对150例患者进行了术后早期(20天)和晚期(13个月)血管造影,以评估乳内动脉(IMA)冠状动脉移植血管的通畅情况。76支右IMA移植血管的早期和晚期失败例数分别为3例和5例,139支左IMA移植血管的早期和晚期失败例数分别为7例和7例,IMA总体通畅率分别为95%和90%。IMA和冠状动脉内径与移植血管闭塞无关。右IMA的自由血流与移植血管闭塞无关。血栓形成的左IMA移植血管的自由血流(91毫升/分钟)显著低于通畅移植血管的自由血流(118毫升/分钟)(P<0.05)。右IMA吻合口血流为55毫升/分钟,显著高于闭塞移植血管的血流26毫升/分钟(P<0.001),左IMA通畅移植血管(55毫升/分钟)和闭塞移植血管(43毫升/分钟)的情况也是如此(P<0.025)。215支IMA移植血管中有5支出现弥漫性狭窄(>50%)。进行了88例大隐静脉冠状动脉搭桥术,早期通畅率为89%(79/88),晚期通畅率为88%(78/88)。38支右冠状动脉静脉移植血管中只有1支失败,而44支旋支动脉移植血管中有8支闭塞。经验的积累使每连续50例患者中IMA晚期通畅率从81%(57/70)提高到89%(68/76),再提高到99%(68/69)。目前,左IMA常规用于左前降支动脉,右IMA很少使用。

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