Guruprasad K, Prasad M S, Kumar G R
Centre for DNA Fingerprinting and Diagnostics (CDFD), Nacharam, Hyderabad - 500 076, India.
Bioinformatics. 2000 Apr;16(4):372-5. doi: 10.1093/bioinformatics/16.4.372.
The database of structural motifs in proteins (DSMP) contains data relevant to helices, beta-turns, gamma-turns, beta-hairpins, psi-loops, beta-alpha-beta motifs, beta-sheets, beta-strands and disulphide bridges extracted from all proteins in the Protein Data Bank primarily using the PROMOTIF program and implemented as a web-based network service using the SRS. The data corresponding to the structural motifs includes; sequence, position in polypeptide chain, geometry, type, unique code, keywords and resolution of crystal structure. This data is available for a representative data set of 1028 protein chains and also for all 10 213 proteins in the Protein Data Bank. The three-dimensional coordinates for all structural motifs (except sheet and disulphide bridge) are also available for the representative data set. Using features in SRS, DSMP can be queried to extract information from one or more structural motifs that may be useful for sequence-structure analysis, prediction, modelling or design.
http://www. cdfd.org.in/dsmp.html
蛋白质结构基序数据库（DSMP）包含与螺旋、β转角、γ转角、β发夹、ψ环、β-α-β基序、β折叠、β链和二硫键相关的数据，这些数据主要从蛋白质数据库（Protein Data Bank）中的所有蛋白质中提取，使用的是PROMOTIF程序，并通过SRS实现为基于网络的服务。与结构基序对应的数据包括：序列、在多肽链中的位置、几何形状、类型、唯一代码、关键词和晶体结构的分辨率。该数据可用于1028条蛋白质链的代表性数据集，也可用于蛋白质数据库中的所有10213种蛋白质。代表性数据集还提供了所有结构基序（β折叠和二硫键除外）的三维坐标。利用SRS中的功能，可以查询DSMP，从一个或多个结构基序中提取可能对序列-结构分析、预测、建模或设计有用的信息。
