PROMOTIF——一个用于识别和分析蛋白质结构基序的程序。
PROMOTIF--a program to identify and analyze structural motifs in proteins.
作者信息
Hutchinson E G, Thornton J M
机构信息
Department of Biochemistry and Molecular Biology, University College, London, United Kingdom.
出版信息
Protein Sci. 1996 Feb;5(2):212-20. doi: 10.1002/pro.5560050204.
Abstract
We describe a suite of programs, PROMOTIF, that analyzes a protein coordinate file and provides details about the structural motifs in the protein. The program currently analyzes the following structural features: secondary structure; beta-and gamma-turns; helical geometry and interactions; beta-strands and beta-sheet topology; beta-bulges; beta-hairpins; beta-alpha-beta units and psi-loops; disulphide bridges; and main-chain hydrogen bonding patterns. PROMOTIF creates postscript files showing the examples of each type of motif in the protein, and a summary page. The program can also be used to compare motifs in a group of related structures, such as an ensemble of NMR structures.
摘要
我们描述了一套名为PROMOTIF的程序，它能分析蛋白质坐标文件并提供有关蛋白质中结构基序的详细信息。该程序目前可分析以下结构特征：二级结构；β-转角和γ-转角；螺旋几何结构及相互作用；β-链和β-折叠拓扑结构；β-凸起；β-发夹结构；β-α-β单元和ψ-环；二硫键；以及主链氢键模式。PROMOTIF会创建PostScript文件，展示蛋白质中每种基序类型的示例以及一个总结页面。该程序还可用于比较一组相关结构（如NMR结构集合）中的基序。
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