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环境医学,第三部分:慢性低剂量汞暴露的长期影响。

Environmental medicine, part three: long-term effects of chronic low-dose mercury exposure.

作者信息

Crinnion W J

机构信息

Healing Naturally, 11811 NE 128th St., Suite 202, Kirkland, WA 98034, USA.

出版信息

Altern Med Rev. 2000 Jun;5(3):209-23.

PMID:10869102
Abstract

Mercury is ubiquitous in the environment, and in our mouths in the form of "silver" amalgams. Once introduced to the body through food or vapor, mercury is rapidly absorbed and accumulates in several tissues, leading to increased oxidative damage, mitochondrial dysfunction, and cell death. Mercury primarily affects neurological tissue, resulting in numerous neurological symptoms, and also affects the kidneys and the immune system. It causes increased production of free radicals and decreases the availability of antioxidants. It also has devastating effects on the glutathione content of the body, giving rise to the possibility of increased retention of other environmental toxins. Fortunately, effective tests are available to help distinguish those individuals who are excessively burdened with mercury, and to monitor them during treatment. Therapies for assisting the reduction of a mercury load include the use of 2,3-dimercaptosuccinic acid (DMSA) and 2,3-dimercato-1-propanesulfonic acid (DMPS). Additional supplementation to assist in the removal of mercury and to reduce its adverse effects is discussed.

摘要

汞在环境中无处不在,并且以“银”汞合金的形式存在于我们的口腔中。一旦通过食物或蒸汽进入人体,汞会迅速被吸收并在多个组织中积累,导致氧化损伤增加、线粒体功能障碍和细胞死亡。汞主要影响神经组织,导致多种神经症状,还会影响肾脏和免疫系统。它会导致自由基产生增加,抗氧化剂的可用性降低。它还会对人体的谷胱甘肽含量产生毁灭性影响,从而增加其他环境毒素滞留的可能性。幸运的是,有有效的测试可帮助区分汞负荷过高的个体,并在治疗期间对其进行监测。协助降低汞负荷的疗法包括使用2,3-二巯基丁二酸(DMSA)和2,3-二巯基-1-丙磺酸钠(DMPS)。还讨论了有助于去除汞并减少其不良影响的额外补充剂。

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