Mautes A E, Weinzierl M R, Donovan F, Noble L J
Neurosurgical Research Laboratory, Saarland University Medical School, Homburg, Germany.
Phys Ther. 2000 Jul;80(7):673-87.
Traumatic spinal cord injury results in the disruption of neural and vascular structures (primary injury) and is characterized by an evolution of secondary pathogenic events that collectively define the extent of functional recovery. This article reviews the vascular responses to spinal cord injury, focusing on both early and delayed events, including intraparenchymal hemorrhage, inflammation, disruption of the blood-spinal cord barrier, and angiogenesis. These vascular-related events not only influence the evolution of secondary tissue damage but also define an environment that fosters neural plasticity in the chronically injured spinal cord.
创伤性脊髓损伤会导致神经和血管结构的破坏（原发性损伤），其特征是继发性致病事件的演变，这些事件共同决定了功能恢复的程度。本文综述了脊髓损伤后的血管反应，重点关注早期和延迟事件，包括实质内出血、炎症、血脊髓屏障破坏和血管生成。这些与血管相关的事件不仅影响继发性组织损伤的演变，还定义了一个促进慢性损伤脊髓神经可塑性的环境。
